Epilepsy is the chronic non-communicable disease of the nervous system most prevalent in the world. Valproic acid (VPA) is one of the most used drugs in the treatment of epilepsy but with various side effects. One of the organs that can be affected is the testis, where it has been seen that men treated w...
SUMMARY: BPA is a multifunctional endocrine disruptor with ubiquitous presence in aquatic ecosystems. The Mexican Central Plateau is an area severely impacted by pollution, inhabited by endemic viviparous fish. However, efforts to understand the effects of BPA on native species such as Goodea atripinnis ...
SUMMARY: Glucose has an essential role in the proliferation and survival of testicular tissue. Glucose transporters (GLUTs) are responsible for glucose uptake across cell membranes. In the present work, two main isoforms GLUT1 and GLUT3 were investigated in the testes of Laboratory mouse (BALB/c), Lesser...
SUMMARY: Testicular descent is a complex process that only occurs in mammals. The role of the gubernaculum during testicular descent has been explained mainly by its capacity for dilatation and contraction. This study tried to investigate the changes in the structure of the fibers and cells of the gubern...
Bisphenol A (BPA) have been reported to induced reprotoxicity in rats. This study was conducted to find out the ameliorative properties of aqueous extract of Cyperus esculentus (tigernut) on BPA induced testicular toxicity in Wistar rats.Methods: Twenty male rats were divided randomly into 4 groups (n=5)...
Enfermedades Testiculares/prevención & control,
Testículo/efectos de los fármacos,
Cyperus/química,
Extractos Vegetales/farmacología,
Extractos Vegetales/aislamiento & purificación,
Enfermedades Testiculares/inducido químicamente,
Enfermedades Testiculares/metabolismo,
Enfermedades Testiculares/patología,
Testículo/metabolismo,
Antiinflamatorios/aislamiento & purificación,
Antiinflamatorios/farmacología,
Antioxidantes/aislamiento & purificación,
Antioxidantes/farmacología,
Modelos Animales de Enfermedad,
Bisfenol A Glicidil Metacrilato/efectos adversos,
Ratas Wistar,
Espermatozoides/efectos de los fármacos,
Espermatozoides/metabolismo,
Espermatozoides/patología
La histoplasmosis es una micosis sistémica producida por una variedad de hongo dimorfo perteneciente al complejo Histoplasma capsulatum. Es una enfermedad prevalente en nuestro medio y sobre todo en pacientes viviendo con HIV con recuento de <200 linfocitos CD4/ml y con cargas virales mayores a 100.000 ...
Introdução: a neoplasia testicular é pouco frequente e o cisto epidermoide é uma lesão benigna rara. A cirurgia poupadora de testículo deve ser realizada quando evidenciada essa lesão no exame de imagem. Relato do caso: homem de 31 anos, com nódulo indolor no testículo esquerdo. A ultrassonograf...
Objective To estimate the incidental radiation dose delivered to the testicles in three dimensional conformal radiotherapy (3DCRT), intensity-modulated radiotherapy (IMRT), and volumetric-modulated arc therapy (VMAT) in rectal cancer patients and its impact on sexual activity using a quality-of-life ques...
SUMMARY: The aim of this study is to reveal the gonadoprotective effects of myricetin (MYC), which has many biological properties, on cisplatin (CP)-induced testicular damage in rats. For this purpose, 40 male Wistar albino rats were divided into 4 groups as Control (group given no treatment), MYC (group...
Flavonoides/administración & dosificación,
Flavonoides/farmacología,
Testículo/lesiones,
Testículo/efectos de los fármacos,
Cisplatino/toxicidad,
Antineoplásicos/toxicidad,
Respuesta al Choque Térmico,
Inflamación,
Ratas Wistar,
Receptor Toll-Like 4,
FN-kappa B,
Inmunohistoquímica,
Etiquetado Corte-Fin in Situ
El ácido valproico (VPA) es un fármaco antiepiléptico teratógenico que, al ser administrado durante etapas tempranas del embarazo, puede producir alteraciones en el desarrollo embriofetal, las que se manifiestan tanto a nivel del sistema nervioso como del testículo. No obstante, se ha reportado que ...
