SUMMARY: Glucose has an essential role in the proliferation and survival of testicular tissue. Glucose transporters (GLUTs) are responsible for glucose uptake across cell membranes. In the present work, two main isoforms GLUT1 and GLUT3 were investigated in the testes of Laboratory mouse (BALB/c), Lesser...
Bisphenol A (BPA) have been reported to induced reprotoxicity in rats. This study was conducted to find out the ameliorative properties of aqueous extract of Cyperus esculentus (tigernut) on BPA induced testicular toxicity in Wistar rats.Methods: Twenty male rats were divided randomly into 4 groups (n=5)...
Enfermedades Testiculares/prevención & control,
Testículo/efectos de los fármacos,
Cyperus/química,
Extractos Vegetales/farmacología,
Extractos Vegetales/aislamiento & purificación,
Enfermedades Testiculares/inducido químicamente,
Enfermedades Testiculares/metabolismo,
Enfermedades Testiculares/patología,
Testículo/metabolismo,
Antiinflamatorios/aislamiento & purificación,
Antiinflamatorios/farmacología,
Antioxidantes/aislamiento & purificación,
Antioxidantes/farmacología,
Modelos Animales de Enfermedad,
Bisfenol A Glicidil Metacrilato/efectos adversos,
Ratas Wistar,
Espermatozoides/efectos de los fármacos,
Espermatozoides/metabolismo,
Espermatozoides/patología
BACKGROUND: Spermatogonial stem cells (SSCs) are critical for sustaining spermatogenesis. Even though several regulators of SSC have been identified in rodents, the regulatory mechanism of SSC in humans has yet to be discovered. METHODS: To explore the regulatory mechanisms of human SSCs, we analyzed pub...
BACKGROUND: The testes are highly susceptible to the adverse effects of chemotherapy and radiation at all stages of life. Exposure to these threats mainly occurs during cancer treatment and as an occupational hazard in radiation centers. The present study investigated the regenerative ability of adipose-...
Azoospermia/inducido químicamente,
Azoospermia/metabolismo,
Azoospermia/patología,
Células Madre Mesenquimatosas,
Antioxidantes/farmacología,
Cisplatino/efectos adversos,
Estrés Oxidativo,
Semen,
Espermatozoides/metabolismo,
Espermatozoides/patología,
Testículo/metabolismo,
Testosterona/farmacología
SUMMARY: Recent studies have shown that homeobox proteins play an important role in the formation and development of tissues and organs in the embryonic period. In our study, the distribution of Dlx-5 and TLX proteins, which are members of the homeobox family, in the testis, epididymis and ductus deferen...
BACKGROUND: Xenotransplantation has been primarily performed using fresh donor tissue to study testicular development for about 20 years, and whether the cultured tissue would be a suitable donor is unclear. In this study, we combined testicular culture and xenotransplantation into an integrative model a...
BACKGROUND: Ionizing radiations (IR) have widespread useful applications in our daily life; however, they have unfavorable effects on reproductive health. Maintaining testicular health following IR exposure is an important requirement for reproductive potential. The current study explored the role of mel...
SUMMARY: Studies have shown the adverse effects of epileptic seizures on reproductive health. The aim of the present study was to investigate morphological changes, apoptosis and GABA localization in the testis tissue of genetic absence epilepsy rats. Testis tissues of GAERS and Wistar rats were processe...
SUMMARY: Diabetes is a metabolic disorder characterized by high blood sugar levels and it causes complications in many systems, including the reproductive system. As a result of diabetic conditions, one of the mechanisms that can cause repression of reproductive activity is testicular oxidant stress. The...
Oligozoospermia is a common infertility disease, and the incidence rate is increasing year by year. Cuscuta chinensis is a commonly used medicine for the treatment of oligozoospermia in Chinese medicine. Flavonoids are its main component. GM-CSF is a multifunctional cytokine that plays an important role ...
