Results: 28

Atovaquone, chloroquine, primaquine, quinine and tetracycline: antiproliferative effects of relevant antimalarials on Neospora caninum

Abstract Neospora caninum is an apicomplexan parasite that causes abortion in cattle, resulting in significant economic losses. There is no commercial treatment for neosporosis, and drug repositioning is a fast strategy to test possible candidates against N. caninum. In this article, we describe the effe...

Informe diário de evidências COVID-19: busca realizada em 4 de agosto de 2020
COVID-19 daily evidence report: search conducted on August 4, 2020

O Informe Diário de Evidências é uma produção do Ministério da Saúde que tem como objetivo acompanhar diariamente as publicações científicas sobre tratamento farmacológico e vacinas para a COVID-19. Dessa forma, são realizadas buscas estruturadas em bases de dados biomédicas, referentes ao d...

New antibiotics against bacterial resistance

Infectio; 23 (4), 2019
The evolution of bacterial resistance is generating a serious public health problem due to the indiscriminate use of antibiotics, the application of non-optimal doses, the irregularity in the taking of medicines sent by the health professional, factors that have affected the increase in the rate of antim...

Acondicionamiento radicular en el tratamiento periodontal no quirúrgico y quirúrgico
Root conditioning in non-surgical and surgical periodontal therapy

Rev. ADM; 76 (5), 2019
La instrumentación mecánica durante el tratamiento periodontal trae consigo la formación de escombros microcristalinos que inhiben la adhesión tisular a la superfi cie radicular y favorece la proliferación bacteriana, lo cual perjudica los resultados del tratamiento periodontal a corto y largo plazo...

Resistencia a los antimicrobianos en Chile y el paradigma de Una Salud: manejando los riesgos para la salud pública humana y animal resultante del uso de antimicrobianos en la acuicultura del salmón y en medicina

Rev. chil. infectol; 35 (3), 2018
El aumento de la resistencia bacteriana múltiple a antimicrobianos es considerado una gran amenaza para la salud pública mundial y como generador de una importante crisis en el funcionamiento de los sistemas de salud. Esta crisis es discutida diariamente por los gobiernos y los parlamentos, las institu...

Changes in weight and body fat after use of tetracycline and Lactobacillus gasseri in rats

ABSTRACT Recent studies have shown a role of intestinal microbiota in obesity. The consumption of antibiotics in the last 70 years has led to changes in intestinal microbiota, which has led to weight gain and body fat accumulation. To evaluate the possibility of weight gain induced by antibiotics and the...

Neutrophil elastase ameliorates matrix metalloproteinase-9 to promote lipopolysaccharide-induced acute lung injury in mice 1

Acta cir. bras; 31 (6), 2016
ABSTRACT PURPOSE: To investigate the regulatory roles of neutrophil elastase (NE) and matrix metalloproteinase-9 (MMP-9) in lipopolysaccharide (LPS)-induced acute lung injury (ALI) in mice. METHODS: To construct LPS-induced ALI mouse models, wild-type C57BL/6 mice were administered 5.0 mg/kg of LPS t...

Tetracycline: production, waste treatment and environmental impact assessment

Braz. j. pharm. sci; 50 (1), 2014
The frequent occurrence of pharmaceuticals in the aquatic environment requires an assessment of their environmental impact and their negative effects in humans. Among the drugs with high harmful potential to the environment are the antibiotics that reach the environment not only, as may be expected, thro...

Nevus blanco esponjoso familiar
Family nevus spongiosus albus

Rev. cuba. estomatol; 47 (2), 2010
El nevus blanco esponjoso (NBE) es una rara condición autosómica dominante, caracterizada por placas blancas bilaterales en la mucosa, de aspecto esponjoso, blandas a la palpación y que pueden escamarse. Los tratamientos son paliativos; y el uso de antibióticos, en especial la tetraciclina, ha demost...

Determinação de tetraciclinas em medicamentos veterinários utilizando análise por injeção em fluxo (FIA)
Determination of tetracyclines in veterinarian medicines by flow injection analysis (FIA)

Rev. bras. toxicol; 17 (2), 2004
Foi desenvolvido um método de análise por injeção em fluxo (FIA) com detector de fluorescência para determinação de oxitetraciclina (OTC), doxiciclina (DC) e tetraciclina (TC) em medicamentos veterinários. O sistema FIA foi otimizado com relação ao carregador (NaOH 2,5 10-3 mol L-1) e vazão (0...