Results: 11

Melhora no Consumo Máximo de Oxigênio e na Ventilação após Tratamento com Sacubitril-Valsartana

Arq. bras. cardiol; 115 (5), 2020
Resumo Fundamento O tratamento com sacubitril-valsartana teve seu benefício prognóstico confirmado no ensaio PARADIGM-HF. No entanto, dados sobre alterações no teste de esforço cardiopulmonar (TECP) com o uso de sacubitril-valsartana são escassos. Objetivo O objetivo deste estudo foi comparar o...

Improved histoarchitectural changes with angiotensin receptor blockers in early testicular and cauda toxicity in rats

Int. j. morphol; 37 (2), 2019
SUMMARY: Reproductive dysfunction is a complication for many diseases and toxins. Its early diagnosis and treatment are immensely important. Here the morphological histoarchitecture changes in early testicular and cauda toxicity before and after treatment with angiotensin receptor blockers were evaluated...

Pacientes elegibles para las nuevas terapias de la insuficiencia cardíaca en un policlínico especializado

Rev. méd. Chile; 147 (3), 2019
Background: Pharmacological treatment improves survival in patients with heart failure with reduced ejection fraction. The use of sacubutril/valsartan and ivabradine has been recently approved and incorporated in the latest guidelines. Aim: To identify candidates eligible for these therapies among patie...

Un novedoso agente en el tratamiento de la insuficiencia cardiaca con función sistólica deprimida

Arch. cardiol. Méx; 88 (4), 2018
Resumen Introducción: Se revisará la evolución del tratamiento farmacológico de la insuficiencia cardiaca (IC) en los últimos 25 an˜os, desde el concepto de tratamiento con vasodilatadores, pasando por el bloqueo o inhibición del sistema renina-angiotensina-aldosterona y la inhibición betaa...

Effect of cilostazol in experimental model of degloving injuries in rat limbs

Acta cir. bras; 33 (4), 2018
Abstract Purpose: To evaluate the effect of the cilostazol on the evolution of partially avulsed flaps, using experimental model of cutaneous degloving in rat limbs. Methods: A controlled and randomized experimental study was carried out in which the blood flow and the percentage of flap necrosis were ...

Safety and efficacy of fimasartan in Mexican patients with grade 1-2 essential hypertension

Arch. cardiol. Méx; 87 (4), 2017
Abstract: Objective: To evaluate efficacy and safety of 60 mg and 120 mg Fimasartan (FMS) alone or combined with 12.5 mg hydrochlorothiazide (HCTZ) in a Mexican population. Methods: A six month, treat-to-target, open study was conducted on subjects with grade 1-2 hypertension. The subjects were initi...

Urinary cytokine profiles according to the site of blockade of the renin-angiotensin system in nephrectomized rats

J. bras. nefrol; 39 (2), 2017
Abstract Introduction: It is still unknown how the pharmacological inhibition of the Renin Angiotensin System (RAS) impacts the levels of inflammation and fibrosis biomarkers. Objective: This study sought to evaluate the effect of enalapril, candesartan and aliskiren on urinary levels of cytokines in a...

La cuádruple combinación de antihipertensivos a bajas dosis tendría un efecto aditivo beneficioso