Effect of melatonin on peripheral nerve damage resulting from tibial defect in rats
Int. j. morphol; 40 (4), 2022
SUMMARY: Peripheral nerve damage (PNI) can cause demyelination, axonal degeneration and loss of motor and sensory function. Melatonin with its antioxidative effect, has been reported to reduce scar formation in nerve injury, take a role in repair process by suppressing fibroblast proliferation in the dam...
Tibia/patología, Enfermedades del Sistema Nervioso Periférico/tratamiento farmacológico, Tibia/inervación, Melatonina/administración & dosificación, Antioxidantes/administración & dosificación, Modelos Animales de Enfermedad, Ratas Wistar, Proteínas S100, Factor A de Crecimiento Endotelial Vascular, Nervios Periféricos/efectos de los fármacos, Fibroblastos