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Distribution and morphology of ghrelin-immunopositive cells in the thymus of the African ostrich

Wang, Jia-xiang; Li, Peng; Zhang, Xiao-ting; Ye, Li-xun.
Int. j. morphol; 35 (2), 2017
Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor, has been detected in the thymus of multiple vertebrates. However, little is known about its distribution in the thymus of the African ostrich. In this study, we evaluated the distribution and morphological characteristics of ghre...
Struthioniformes, Timo/metabolismo, Ghrelina/metabolismo, Inmunohistoquímica, Timo/anatomía & histología
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Growth hormone in the presence of laminin modulates interaction of human thymic epithelial cells and thymocytes in vitro

Lins, Marvin Paulo; Vieira, Larissa Fernanda de Araújo; Rosa, Alfredo Aurélio Marinho; Smaniotto, Salete.
Biol. Res; 49 (), 2016
BACKGROUND: Several evidences indicate that hormones and neuropeptides function as immunomodulators. Among these, growth hormone (GH) is known to act on the thymic microenvironment, supporting its role in thymocyte differentiation. The aim of this study was to evaluate the effect of GH on human thymocyte...
Células Epiteliales/efectos de los fármacos, Hormona del Crecimiento/farmacología, Laminina/biosíntesis, Timocitos/efectos de los fármacos, Timo/citología, Adhesión Celular/efectos de los fármacos, Diferenciación Celular/efectos de los fármacos, Movimiento Celular/efectos de los fármacos, Citometría de Flujo/métodos, Integrina alfa6beta1/análisis, Integrina alfa6beta1/metabolismo, Laminina/efectos de los fármacos, Timo/metabolismo, Análisis de Varianza, Linfocitos T CD4-Positivos, Linfocitos T CD8-positivos, Células Cultivadas, Técnicas de Cocultivo, Inmunohistoquímica, Valores de Referencia, Factores de Tiempo
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