Objetivo: verificar a toxicidade do uso medicamentoso da hidroxicloroquina em pacientes. Metodologia: trata-se de uma revisão integrativa de literatura com uma avaliação documental e abordagem descritiva nas bases de dados eletrônicos LILACS, SCIELO e MEDLINE-PUBMED, usando diferentes combinações d...
Objetivo: Analizar la resistencia a la corrosión por picaduras de aceros inoxidables AISI 304 y AISI 420 en un medio que contiene cloruros (solu-ción de NaCl al 0,9 y 3,5%, en masa), así como su citotoxicidad, in vitro, en muestras con y sin corrosión por picaduras. Método: Estudio experimental. Se ...
The active ingredient glyphosate is the most commercialized herbicide on the world market due to its capability in eliminating weeds. However, it can harm the development of non-target organisms and threaten environmental quality. This study analyzed the effects of potentially toxic concentrations of gly...
Objetivo: Verificar que los recolectores de orina no son tóxicos para los espermatozoides. Métodos: Se evaluó la toxicidad de recipientes de material de vidrio (control) y plástico (recolector de orina) con muestras de semen de buena concentración y movilidad de espermatozoides, mediante el estudio ...
Oliveira, Leilanne Márcia Nogueira de;
Bastos, Maria do Socorro Rocha;
Lima, Ana Cristina Silva de;
Figueiredo, Evânia Altina Teixera de;
Dias, Flayanna Gouveia Braga;
Silva, Larissa Morais Ribeiro da;
Benevides, Selene Dahia;
Ribeiro, Paulo Riceli Vasconcelos;
Sabino, Luiz Bruno de Sousa;
Figueiredo, Raimundo Wilane de.
Abstract In this research, aqueous and ethanolic extracts from Justicia pectoralis Jacq and Croton Jacobinensis Baill were characterized. The UPLC-QTOF-MSE analysis was performed on the extracts identified, predominantly, flavonoids, tannins and acids. The extracts did not indicate toxicity in human epit...
Abstract Prolonged overexposure to catecholamines causes toxicity, usually credited to continuous adrenoceptor stimulation, autoxidation, and the formation of reactive pro-oxidant species. Non-differentiated SH-SY5Y cells were used to study the possible contribution of oxidative stress in adrenaline (ADR...
Neuronas/clasificación,
Toxicidad,
Epinefrina/agonistas,
Antioxidantes/farmacología,
Bromuros/antagonistas & inhibidores,
d0024770,
Enfermedades del Sistema Nervioso Periférico/clasificación,
Estrés Oxidativo/efectos de los fármacos,
d0077700,
Nervios Periféricos/anomalías,
d0119410
Purpose: We aimed to investigate the antioxidant activity of nebivolol against possible damage to the ovarian tissue due to the application of deltamethrin as a toxic agent, by evaluating histopathological proliferating cell nuclear antigen (PCNA) and tumor necrosis factor-alpha (TNF-α) signal molecules...
Lamb, Liliane Weber Bolfe;
Rodrigues, Gabriela Zimmermann Prado;
Saraiva, Thalia Emmanoella Sebulsqui;
Souza, Douglas de;
Berna, Gabriel da Costa;
Garcia, Ana Letícia Hilário;
Oliveira, Fernando Bertoldi de;
Kayser, Juliana Machado;
Veiverberg, Andriele;
Marco, Mariana Roza;
Führ, Giulia Aline;
Gehlen, Günther;
Betti, Andresa Heemann;
Mattos, Cristiane Bastos de.
Abstract Resolution 658/2022 of the Brazilian Regulatory Agency requires the determination of the permitted daily exposure (PDE) of pharmaceutical agents. Ginkgo biloba L. is used therapeutically to treat memory deficits and other brain diseases. However, published results indicate that more studies are ...
Abstract Over the years, a handful of drugs have been approved to be used in the fight against Alzheimer's Disease but unfortunately none of these drugs have proven to be solid-treatments. Alzheimer's Disease is one of the most prominent diseases observed in the elderly population. In this review article...
