Fruit ripening is a biochemical process that results in flavor, odor, texture, and color suitable for human consumption, in addition to providing access to important nutrients. Although ripening promotes sensory and nutritional increases in fruits, there is also an increased susceptibility to physical da...
BACKGROUND Forty percent of the world's population live in areas where they are at risk from dengue fever, dengue hemorrhagic fever, and dengue shock syndrome. Dengue viruses are transmitted primarily by the mosquito Aedes aegypti. In Cali, Colombia, approximately 30% of field collected Ae. aegypti are ...
BACKGROUND: To identify differentially expressed genes (DEGs) between muscle and adipose in cattle, we analyzed the data from the RNA sequencing of three Angus×Qinchuan crossbred cattle. RESULTS: Searched the Gene Expression Omnibus (GEO) for a microarray dataset of Yan yellow cattle, GSE49992. After th...
Cardoso, Thaís Cunha de Sousa;
de Araújo, Carlos Bruno;
Portilho, Laysa Gomes;
Mendes, Luiz Guilherme Alves;
Alves, Tamires Caixeta;
Silva, Gustavo Caetano;
Ribeiro, Thales Henrique Cherubino;
Gandolfi, Peterson Elizandro;
Morais, Enyara Rezende;
do Amaral, Laurence Rodrigues;
Gomes, Matheus de Souza.
BACKGROUND Key genes control the infectivity of the Schistosoma haematobium causing schistosomiasis. A method for understanding the regulation of these genes might help in developing new disease strategies to control schistosomiasis, such as the silencing mediated by microRNAs (miRNAs). The miRNAs have ...
BACKGROUND The leishmaniases are complex neglected diseases caused by protozoan parasites of the genus Leishmania. Leishmania braziliensis is the main etiological agent of cutaneous leishmaniasis in the New World. In recent studies, genomic changes such as chromosome and gene copy number variations (CNV...
Abstract Synthetic polyploids are key breeding materials for watermelon. Compared with diploid watermelon, the tetraploid watermelon often exhibit wide phenotypic differences and differential gene expression. Digital gene expression (DGE) profile technique was performed in this study to present gene exp...
A fumaça do cigarro apresenta mais de 8700 substâncias identificadas, as quais já foram relacionadas com o desenvolvimento das mais variadas doenças. Dentre elas, uma substância relevante neste contexto de toxicidade do cigarro é a hidroquinona (HQ), gerada após a biotransformação do benzeno ina...
Aortic dissection is characterized by the redirection of blood flow, which flows through an intimal tear into the aortic media. The purpose of this study was to find potential acute type A aortic dissection (AAAD)-related genes and molecular mechanisms by bioinformatics. The gene expression profiles of G...
Viscarra, Tamara;
Buchegger, Kurt;
Jofre, Ignacio;
Riquelme, Ismael;
Zanella, Louise;
Abanto, Michel;
Parker, Alyssa C;
Piccolo, Stephen R;
Roa, Juan Carlos;
Ili, Carmen;
Brebi, Priscilla.
BACKGROUND: Ovarian cancer is a significant cancer-related cause of death in women worldwide. The most used chemotherapeutic regimen is based on carboplatin (CBDCA). However, CBDCA resistance is the main obstacle to a better prognosis. An in vitro drug-resistant cell model would help in the understanding...
Antineoplásicos/farmacología,
Carboplatino/farmacología,
Resistencia a Antineoplásicos/genética,
Regulación Neoplásica de la Expresión Génica/efectos de los fármacos,
Neoplasias Ováricas/genética,
Transcriptoma/efectos de los fármacos,
Muerte Celular/efectos de los fármacos,
Muerte Celular/genética,
Neoplasias Ováricas/tratamiento farmacológico,
Neoplasias Ováricas/patología,
Transcriptoma/genética,
Línea Celular Tumoral,
Fenotipo,
Análisis de Secuencia de ARN,
Transducción de Señal
Background: Soil salinity can significantly reduce crop production, but the molecular mechanism of salinity tolerance in peanut is poorly understood. A mutant (S1) with higher salinity resistance than its mutagenic parent HY22 (S3) was obtained. Transcriptome sequencing and digital gene expression (DGE) ...
