LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Protective Autophagy in 5-Fluorouracil-Resistant Colorectal Cancer Cells and ERK-RSK-ABCG2 Linkage

Yoon, Sang-Pil.

Int. j. morphol; 41 (6), 2023

SUMMARY: To evaluate the anti-cancer effects of yeast extract on resistant cells, autophagy and necroptosis were investigated in 5-fluorouracil (5-FU)-resistant colorectal cancer cells. Further underlying characteristics on drug resistance were evaluated, focused on ERK-RSK-ABCG2 linkage. SNU-C5 and 5-FU...

Extractos Vegetales/farmacología, Neoplasias Colorrectales/tratamiento farmacológico, Resistencia a Antineoplásicos, Fluorouracilo, Autofagia, Antineoplásicos/farmacología, Proteínas Quinasas S6 Ribosómicas 90-kDa, Transportador de Casetes de Unión a ATP, Subfamilia G, Miembro 2, Células Tumorales Cultivadas, Levaduras, Necroptosis, Supervivencia Celular/efectos de los fármacos, Western Blotting, Electroforesis

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ABCG2 polymorphism, age and leukocyte count may contribute to oral mucositis in oncopediatric patients

Viana Filho, José Maria Chagas; Coêlho, Marina de Castro; Ribeiro, Isabella Lima Arrais; Persuhn, Darlene Camati; Valença, Ana Maria Gondim; Oliveira, Naila Francis Paulo de.

Braz. dent. j; 32 (2), 2021

Abstract The study investigated the relationship between genetic polymorphisms and the development of oral mucositis in pediatric patients undergoing chemotherapy involving methotrexate. A longitudinal study was conducted with 64 patients, and oral mucositis was evaluated by the modified Oral Assessment ...

Transportador de Casetes de Unión a ATP, Subfamilia G, Miembro 2/genética, Recuento de Leucocitos, Estudios Longitudinales, Proteínas de Neoplasias/genética, Polimorfismo Genético, Estomatitis/genética

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Evidence of progenitor cells in the adult human cochlea: sphere formation and identification of ABCG2

Massucci-Bissoli, Milene; Lezirovitz, Karina; Oiticica, Jeanne; Bento, Ricardo Ferreira.

Clinics; 72 (11), 2017

OBJECTIVES: The aim of this study was to search for evidence of stem or progenitor cells in the adult human cochlea by testing for sphere formation capacity and the presence of the stem cell marker ABCG2. METHODS: Cochleas removed from patients undergoing vestibular schwannoma resection (n=2) and from b...

Transportador de Casetes de Unión a ATP, Subfamilia G, Miembro 2/análisis, Proliferación Celular, Cóclea/citología, Citometría de Flujo, Proteínas de Neoplasias/análisis, Células Madre/citología

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