SUMMARY: Volume abnormalities in subcortical structures, including the hippocampus, amygdala, thalamus, caudate, putamen, and globus pallidus have been observed in schizophrenia (SZ) and bipolar disorder (BD), not all individuals with these disorders exhibit such changes. In addition, the specific patter...
Objective: The increased prevalence rate of white matter hyperintensities is one of the most consistently reported brain abnormalities in adults with bipolar disorder. However, findings in children and adolescents with bipolar disorder are less consistent. Prior studies have been constrained by small sam...
Bipolar disorder (BD) is a chronic mental illness characterized by changes in mood that alternate between mania and hypomania or between depression and mixed states, often associated with functional impairment. Although effective pharmacological and non-pharmacological treatments are available, several p...
Abstract Background Optical coherence tomography (OCT) has been recently used to investigate neuropsychiatric disorders. Objective The aim of this study was to compare the retinal nerve fiber layer thickness (RNFLT) and the ganglion cell layer (GCL) volume in patients with type 1 bipolar disorder (BP...
Tomografía de Coherencia Óptica,
Trastorno Bipolar/diagnóstico por imagen,
Fibras Nerviosas/patología,
Células Ganglionares de la Retina/patología,
Escalas de Valoración Psiquiátrica,
Encuestas y Cuestionarios,
Entrevista Psicológica,
Enfermedades Neurodegenerativas/diagnóstico por imagen,
Análisis de Regresión,
Compuestos de Litio/uso terapéutico,
Ácido Valproico/uso terapéutico,
Trastorno Bipolar/tratamiento farmacológico,
Enfermedades Neurodegenerativas/prevención & control,
Antimaníacos/uso terapéutico,
Ácido Valproico/farmacología,
Compuestos de Litio/farmacología,
Antimaníacos/farmacología
Abstract Introduction: Bipolar disorder (BD) is a debilitating mood condition that affects approximately 1.3% of people worldwide, although some studies report up to 3.9% lifetime prevalence and 4-6% in adults when broad diagnostic criteria are applied. Objective: To compare differences in total white ...
Trastorno Bipolar/diagnóstico por imagen,
Trastorno Bipolar/patología,
Estudios de Casos y Controles,
Cuerpo Calloso/diagnóstico por imagen,
Cuerpo Calloso/patología,
Progresión de la Enfermedad,
Sustancia Gris/diagnóstico por imagen,
Sustancia Gris/patología,
Imagen por Resonancia Magnética,
Persona de Mediana Edad,
Tamaño de los Órganos,
Sustancia Blanca/diagnóstico por imagen,
Sustancia Blanca/patología
Recently, attention in the field of bipolar disorder (BD) has focused on prevention, including early detection and intervention, as these strategies have the potential to delay, lessen the severity, or even prevent full-blown episodes of BD. Although knowledge of the neurobiology of BD has advanced subst...
Objective: To review the available data on diffusion tensor imaging (DTI) of subjects with bipolar disorder (BD), with a particular focus on fractional anisotropy (FA) in white matter (WM) tracts. Methods: The PubMed/MEDLINE database was searched for relevant articles, which were included in a systemati...
Objective: Approximately one-half of all patients affected by bipolar disorder present with psychotic features on at least one occasion. Several studies have found that alterations in the activity of mesolimbic and prefrontal regions are related to aberrant salience in psychotic patients. The aim of the ...
Trastorno Bipolar/complicaciones,
Trastorno Bipolar/diagnóstico por imagen,
Trastorno Bipolar/fisiopatología,
Corteza Cerebral/diagnóstico por imagen,
Corteza Cerebral/fisiopatología,
Estudios Transversales,
Sustancia Gris/diagnóstico por imagen,
Sustancia Gris/patología,
Alucinaciones/complicaciones,
Alucinaciones/fisiopatología,
Imagen por Resonancia Magnética,
Persona de Mediana Edad,
Tamaño de los Órganos
