Neurochemical and behavioral characterization of neuronal glutamate transporter EAAT3 heterozygous mice
Biol. Res; 50 (), 2017
BACKGROUND: Obsessive-compulsive disorder (OCD) is a severe neuropsychiatric condition affecting 1-3% of the worldwide population. OCD has a strong genetic component, and the SLC1A1 gene that encodes neuronal glutamate transporter EAAT3 is a strong candidate for this disorder. To evaluate the impact of r...
Transportador 3 de Aminoácidos Excitadores/metabolismo, Ácido Glutámico/metabolismo, Trastorno Obsesivo Compulsivo/metabolismo, Transportador 3 de Aminoácidos Excitadores/genética, Ácido Glutámico/genética, Trastorno Obsesivo Compulsivo/genética, Modelos Animales de Enfermedad, Genotipo, Heterocigoto