Results: 5

Neurochemical and behavioral characterization of neuronal glutamate transporter EAAT3 heterozygous mice

Biol. Res; 50 (), 2017
BACKGROUND: Obsessive-compulsive disorder (OCD) is a severe neuropsychiatric condition affecting 1-3% of the worldwide population. OCD has a strong genetic component, and the SLC1A1 gene that encodes neuronal glutamate transporter EAAT3 is a strong candidate for this disorder. To evaluate the impact of r...

Symmetry symptoms in obsessive-compulsive disorder: clinical and genetic correlates

Objective: In obsessive-compulsive disorder (OCD), symmetry-related symptoms may be important. Although clinical correlates of symmetry-related symptoms have been identified in OCD, few data exist on genetic associations. Animal studies indicate involvement of dopamine in symmetry-related behavior, sugge...

Transtorno obsessivo-compulsivo
Obsessive-compulsive disorder

O transtorno obsessivo-compulsivo (TOC) é um quadro psiquiátrico caracterizado pela presença de obsessões e compulsões. Sua prevalência é de aproximadamente 2 por cento a 3 por cento na população geral. Os fatores genéticos estão provavelmente implicados na etiologia do transtorno. Os estudos ...

Transtorno obsessivo-compulsivo em paciente com sindrome de Tourette e febre reumatica sem coreia de Sydenham

Os autores descrevem um caso inedito de transtorno obsessivo-compulsivo (TOC) em paciente com sindrome de Tourette (ST) e febre reumatica (FR) sem coreia de Sydenham (CS), com inicio dos tiques no comeco da infancia. Discutem os possiveis mecanismos fisiopatologicos implicados nessa associacao...

Obsessive-compulsive disorder and Tourette Syndrome: is there a relationship?

Säo Paulo med. j; 115 (2), 1997
The authors describe the main characteristics of Obsessive-Compulsive Disorder, the fourth most frequent psychiatric disease, and Tourette Syndrome. Considered completely separate disorders, there is growing scientific evidence that there is a connection between them. The authors present clinical, geneti...