LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

High frequency of Y chromosome microdeletions in male infertility patients with 45,X/46, XY mosaicism

The mosaic 45,X/46,XY karyotype is a common sex chromosomal abnormality in infertile men. Males with this mosaic karyotype can benefit from assisted reproductive therapies, but the transmitted abnormalities contain 45,X aneuploidy as well as Y chromosome microdeletions. The aim of this study was to inves...

Incidence of Y-chromosome microdeletions in children whose fathers underwent vasectomy reversal or in vitro fertilization with epididymal sperm aspiration: a case-control study

Ghirelli-Filho, Milton; Marchi, Patricia Leme de; Mafra, Fernanda Abani; Cavalcanti, Viviane; Christofolini, Denise Maria; Barbosa, Caio Parente; Bianco, Bianca; Glina, Sidney.

Einstein (Säo Paulo); 14 (4), 2016

ABSTRACT Objective To evaluate the incidence of Y-chromosome microdeletions in individuals born from vasectomized fathers who underwent vasectomy reversal or in vitro fertilization with sperm retrieval by epididymal aspiration (percutaneous epididymal sperm aspiration). Methods A case-control study c...

Fertilización In Vitro, Infertilidad Masculina/epidemiología, Trastornos de los Cromosomas Sexuales del Desarrollo Sexual/epidemiología, Recuperación de la Esperma, Vasovasostomía/efectos adversos, Azoospermia/genética, Brasil/epidemiología, Estudios de Casos y Controles, Deleción Cromosómica, Cromosomas Humanos Y/genética, Padre, Incidencia, Infertilidad Masculina/genética, Aberraciones Cromosómicas Sexuales, Trastornos de los Cromosomas Sexuales del Desarrollo Sexual/genética, Inyecciones de Esperma Intracitoplasmáticas

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