LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud | LILACS

Results: 44

Effects of Adipose-derived Stem Cells in the Treatment of Knee Osteoarthritis: A Case Report in Brazil's Unified Health System

Abstract Osteoarthritis (OA) can incapacitate the individual to perform their activities of daily living due to pain. This is an important public health issue that worsens worldwide and in Brazil, since the population goes through an aging process, and has caused increased public spending on the monitori...

Tratamiento de recaída de leucemia linfoblástica aguda en pacientes pediátricos
Treatment of Relapse in Pediatric Patients with Acute Lymphoblastic Leukemia in Argentina: Results from a Clinical Trial and a Prospective Cohort

Effects of lipografts in immune-driven lipoatrophies. Case studies

Rev. colomb. reumatol; 29 (4), 2022
Lipodystrophy is a pathological condition associated with an abnormal body adipose tissue redistribution. Facial lipoatrophy can be a consequence of congenital, acquired, or involutional. The lipograft is an autologous fat transplant, which constitutes a treatment option that provides volume, tissue rege...

Terapia com células CAR-T: reprogramação celular para o combate de neoplasias malignas

As células CAR-T são linfócitos geneticamente modificados para reconhecerem um espectro amplo de antígenos de superfície celulares. Além disso, atacam células tumorais malignas, que expressam esses antígenos, por meio da ativação da coestimulação citoplasmática, secreção de citocinas, citÃ...

Ética en el ámbito de la investigación en medicina regenerativa
Ethics in the field of regenerative medicine research

Introducción: La medicina regenerativa se basa en la sustitución o regeneración de células humanas, tejidos u órganos con la finalidad de restablecer una función normal. Es una terapia basada en el tratamiento con células madre. Las estrategias terapéuticas basadas en la terapia celular permiten ...

Coautorias nas publicações brasileiras sobre medicina regenerativa: assimetrias na colaboração científica internacional

RECIIS (Online); 15 (4), 2021
A cooperação científica internacional tornou-se um fator essencial para que os países emergentes alcancem novos patamares de pesquisa, publicações e financiamento. No contexto de uma discussão analítica sobre a cooperação científica global, foram analisadas as publicações brasileiras indexad...

Empleo de células madre mononucleares en el tratamiento de osteoartritis en rodilla: caso de estudio en Cuba

Resumen Introducción: el desarrollo alcanzado en la medicina regenerativa posibilita el tratamiento de enfer medades incurables o que tienen una respuesta reducida a las terapéuticas actuales, así como la dis minución del consumo de medicamentos, en algunos casos. En Cuba, las especialidades de ang...

Cell therapy in the treatment of intervertebral disc degeneration

Coluna/Columna; 20 (2), 2021
ABSTRACT Approximately 80% of the world population experiences some type of back pain at some point in their life, and in 10% of this population the pain causes chronic disability resulting in a high cost for the treatment of these patients, in addition to compromising their work and social interaction a...

Obtención de plasma rico en plaquetas (PRP) en el Laboratorio de Terapia Celular para uso como herramienta terapéutica en medicina regenerativa
Obtaining platelet rich plasma (PRP) in the Cell Therapy Laboratory for use as a therapeutic tool in regenerative medicine

Platelet rich plasma (PRP) is used to speed up tissue repair. Despite its widespread use, the therapeutic application of PRP generates controversies in clinical results due to the variability in methods of obtaining the different preparations and differences between the components of different types of P...

Stem cell therapy targets the neointimal smooth muscle cells in experimentally induced atherosclerosis: involvement of intracellular adhesion molecule (ICAM) and vascular cell adhesion molecule (VCAM)

Braz. j. med. biol. res; 54 (8), 2021
Smooth muscle cells (SMCs) are currently considered a central pivotal player in pathogenesis and development of atherosclerotic lesions. As consequence of vascular injury, SMCs migrate from the tunica media into the tunica intima layers where they contribute to neointimal formation by converting into foa...