CD77 levels over enzyme replacement treatment in Fabry Disease Family (V269M)
J. bras. nefrol; 40 (4), 2018
ABSTRACT Introduction: Fabry disease (FD) is a disorder caused by mutations in the gene encoding for lysosomal enzyme α-galactosidase A (α-GAL). Reduced α-GAL activity leads to progressive accumulation of globotriaosylceramide (Gb3), also known as CD77. The recent report of increased expr...