Results: 3

Propranolol inhibits myocardial infarction-induced brown adipose tissue D2 activation and maintains a low thyroid hormone state in rats

Braz. j. med. biol. res; 52 (10), 2019
Considering the recognized role of thyroid hormones on the cardiovascular system during health and disease, we hypothesized that type 2 deiodinase (D2) activity, the main activation pathway of thyroxine (T4)-to-triiodothyronine (T3), could be an important site to modulate thyroid hormone status, which wo...

Thyroxine increases Serca2 and Ryr2 gene expression in heart failure rats with euthyroid sick syndrome

ABSTRACT Objective The current study was aimed at analyzing sarcoplasmic reticulum Ca2+ ATPase (Serca2) and ryanodine receptor type 2 (Ryr2) gene expression in rats subjected to surgery that induced HF and were subsequently treated with T4 using physiological doses. Materials and methods HF was induc...

Alterations of the rat thyroid gland under experimental conditions

The thiyroid gland of rats, was studied under experimental conditions porvided by administration of several doses of lithium carbonate. It was noted a drug a cumulative effcct on the serum; and the decrease of T3 and T4 hormones in the blood, as well as, the red blood cells, hemoglobin, hematocrit platel...