Results: 6

Compromiso renal y digestivo en infecciones por COVID-19

Resumen La infección por el síndrome respiratorio agudo severo (SARS-CoV-2) ha causado una de las emergencias epidemiológicas más grandes de los últimos 10 años y sus efectos patológicos son aún estudiados. Por lo anterior, resulta importante describir los mecanismos asociados al compromiso renal...

Role of SARS-CoV-2 neurotropism and neuroinvasion in COVID-19 patients disease severity

Gac. méd. Méx; 156 (4), 2020
Abstract The disease caused by the new SARS-CoV-2 coronavirus (COVID-19) spread rapidly from China to the entire world. Approximately one third of SARS-CoV-2-infected patients have neurological disorders, especially those classified as severe cases and that require mechanical ventilation. On the other ha...

Cutaneous susceptibility to SARS-CoV-2 infection according to the expression of viral entry factors in the skin

Gac. méd. Méx; 156 (4), 2020
Abstract Introduction: Reports of dermatological manifestations in patients with COVID-19 suggest a possible cutaneous tropism of SARS-CoV-2; however, the capacity of this virus to infect the skin is unknown. Objective: To determine the susceptibility of the skin to SARS-CoV-2 infection based on the ex...

Nicotinamide activates latent HIV-1 ex vivo in ART suppressed individuals, revealing higher potency than the association of two methyltransferase inhibitors, chaetocin and BIX01294

Braz. j. infect. dis; 24 (2), 2020
ABSTRACT Background: Latent HIV-1 is a major hurdle in obtaining HIV-1 sustained virological remission (SVR). Here we explored histone deacetylation inhibition property of nicotinamide (NAM; n = 17) for the first time in comparison to a combination of methyltransferase inhibitors (MTIs; Chaetocin and BI...

Profile of HIV subtypes in HIV/HBV- and HIV/HCV-coinfected patients in Southern Brazil

Abstract INTRODUCTION: HIV and viral hepatitis infections are major causes of chronic disease worldwide and have some similarities with regard to routes of transmission, epidemiology, front barriers faced during access of treatment, and strategies for a global public health response. The objective was t...

Eficacia y seguridad del uso de maraviroc para el tratamiento de VIH-1 con tropismo ccr5 positivo, en pacientes multidrogorresistentes en estadio sida

INTRODUCCIÓN: Antecedentes: El presente dictamen presenta la evaluación de tecnología de la eficacia y seguridad de maraviroc para el tratamiento de pacientes infectados con VIH01 con tropismo CCR5 positivo, multidrogorresistentes, en estadio SIDA. Aspectos Generales: Hacia el final de 2014, alrededor...