Results: 6

Synthetic ligustrazine based cyclohexanone and oxime analogs as Anti-Trypanosoma and Anti-Leishmanial agentes

In the present study a series of 34 synthetic ligustrazine-containing α, β-Unsaturated carbonyl-based compounds and oximes, recognized as anticancer compounds were assessed against protozoa of the Trypanosoma and Leishmania species. Ligustrazine, chemically known as tetramethylpyrazine (TMP), was selec...

Occurrence of triatomines in an urban residential complex in the municipality of Rio Branco, Acre, South-Western Amazon

Abstract INTRODUCTION: This study describes the occurrence of triatomines, and their positivity for trypanosomatids, in a residential complex in Rio Branco, Acre, Brazil. METHODS: Triatomines were collected through direct capture in a home environment. Positivity analysis for trypanosomatids was perf...

Survey of trypanosoma (kinetoplastida: trypanosomatidae) infection in Monte Negro Municipality, State of Rondônia, western amazon, with first record of T. evansi in the state

Abstract INTRODUCTION: Trypanosomes can infect humans and animals. This is the first record of the occurrence of Trypanosoma evansi in Rondônia. METHODS: Blood samples were collected from 7 dogs and 22 humans. Furthermore, triatomines and tabanids were collected. RESULTS: It was observed that 42.8%...

Genetic diversity and molecular survey of Trypanosoma (Megatrypanum ) theileri in cattle in Brazil's western Amazon region

Abstract Trypanosoma (Megatrypanum) theileri is a flagellated protozoan that infects ruminants and it displays high genetic diversity. In this study, we investigated the prevalence rates of this protozoan based on hemoculture and molecular diagnosis. The isolates of T. theileri thus obtained were charact...

Bat trypanosomes from Tapajós-Arapiuns Extractive Reserve in Brazilian Amazon

Abstract Trypanosoma comprises flagellates able to infect several mammalian species and is transmitted by several groups of invertebrates. The order Chiroptera can be infected by the subgenera Herpetosoma, Schizotrypanum, Megatrypanum and Trypanozoon. In this study, we described the diversity of bat tryp...

Caracterización de las cepas de Trypanosoma colombianas por medio de isoenzimas y reacción en cadena de la polimersa y su relación con el origen de aislamiento y procedencia geográfica

Se analizaron 42 cepas de trypanosoma provenientes de los bancos del CIMPAT y del INS, provenientes de varios sitios de Colombia y aislada de diferentes vertebrados (humanos, D. marsupialis, C. Lanatus R. rattus, Aotus sp. y murciélago) o de diferentes vectores (R prolixus, P. geniculatus y Triatoma sp)...