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Genome-wide identification, characterisation and expression profiling of the ubiquitin-proteasome genes in Biomphalaria glabrata

Portilho, Laysa Gomes; Duarte, Bruna Custódio Dias; Queiroz, Fábio Ribeiro; Ribeiro, Thales Henrique Cherubino; Jeremias, Wander de Jesus; Babá, Elio Hideo; Coelho, Paulo Marcos Zech; Morais, Enyara Rezende; Cabral, Fernanda Janku; Caldeira, Roberta Lima; Gomes, Matheus de Souza.
Mem. Inst. Oswaldo Cruz; 114 (), 2019
BACKGROUND Biomphalaria glabrata is the major species used for the study of schistosomiasis-related parasite-host relationships, and understanding its gene regulation may aid in this endeavor. The ubiquitin-proteasome system (UPS) performs post-translational regulation in order to maintain cellular prote...
Biomphalaria/parasitología, Estudio de Asociación del Genoma Completo/métodos, Complejo de la Endopetidasa Proteasomal, Ubiquitina/análisis
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The canonical wnt pathway in gastric carcinoma

Oliveira, Levindo Alves de; Oshima, Celina Tizuko Fujiyama; Soffner, Pedro Augusto; Silva, Marcelo de Souza; Lins, Rodrigo Rego; Malinverni, Andréa Cristina de Moraes; Waisberg, Jaques.
ABCD (São Paulo, Impr.); 32 (1), 2019
ABSTRACT Background : It is believed that the Wnt pathway is one of the most important signaling involved in gastric carcinogenesis. Aim : To analyze the protein expression of canonical and non-canonical Wnt pathways in gastric carcinoma. Method : The immunohistochemistry was performed in 72 specimen...
Proteína Axina/análisis, Carcinogénesis, Carcinoma/química, Carcinoma/patología, Quinasa de la Caseína I/análisis, Ciclina D1/análisis, Receptores Frizzled/análisis, Glucógeno Sintasa Quinasa 3 beta/análisis, Inmunohistoquímica, Proteínas de Neoplasias/análisis, Estadificación de Neoplasias, Proteínas Proto-Oncogénicas c-myc/análisis, Valores de Referencia, Neoplasias Gástricas/química, Neoplasias Gástricas/patología, Ubiquitina/análisis, Vía de Señalización Wnt, Proteína Wnt-5a/análisis
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