Daphnetin inhibits proliferation and inflammatory response in human HaCaT keratinocytes and ameliorates imiquimod-induced psoriasis-like skin lesion in mice
Biol. Res; 53 (), 2020
BACKGROUND: Psoriasis is a common chronic inflammatory skin disease. Keratinocytes hyperproliferation and excessive inflammatory response contribute to psoriasis pathogenesis. The agents able to attenuate keratinocytes hyper-proliferation and excessive inflammatory response are considered to be potential...
Adyuvantes Inmunológicos/efectos adversos, Antiinflamatorios/farmacología, Imiquimod/efectos adversos, Inflamación/tratamiento farmacológico, Psoriasis/inducido químicamente, Psoriasis/tratamiento farmacológico, Umbeliferonas/farmacología, Proliferación Celular, Queratinocitos, Ratones Endogámicos BALB C