Abstract Introduction: Snakes of the genus Micrurus have fossorial habits, passive temperament and scarce production of powerful venom with neurotoxic characteristics that block the synaptic transmission at the neuromuscular junction. Objective: To present an overview of the neurotoxicity of the Micrur...
Abstract Introduction: The association between local anesthetics (LA) and neuromuscular blocking (NMB) drugs in clinical practice, and the possibility of interaction between these drugs has been investigated. LAs act on neuromuscular transmission in a dose-dependent manner and may potentiate the effects...
La miastenia gravis es una enfermedad neuromuscular crónica debida a deficiencia de transmisión nerviosa en la unión neuromuscular, de origen generalmente autoinmune
en el adulto, que se caracteriza por grados variables de debilidad de los músculos esqueléticos del cuerpo, que aumenta durante los p...
Upper limb performance is affected by diabetes mellitus (DM). Neuromuscular junction (NMJ) is a key structure to understand the relationship between performance and morphology in DM. The aim of the study was to analyze NMJ plasticity due to DM in an animal model and its relationship with the function of ...
Abstract Objective To evaluate the neuromuscular junctions (NMJs) and the type of muscle fibers of the soleus muscle of oophorectomized Wistar rats submitted to a mechanical vibration protocol. Methods A total of 36 randomized rats were used in the pseudo-oophorectomy without and with treatment and oop...
Abstract Purpose: To evaluate the effects of duodenal-jejunal bypass (DJB) on the diaphragm muscle of obese rats fed on a western diet (WD) . Methods: Eighteen male Wistar rats were fed a standard rodent chow diet (CTL group) or WD ad libitum. After 10 weeks, WD rats were submitted to sham (WD SHAM) or...
Diafragma/ultraestructura,
Dieta Occidental,
Duodeno/cirugía,
Yeyuno/cirugía,
Unión Neuromuscular/ultraestructura,
Obesidad/cirugía,
Anastomosis Quirúrgica,
Fibras Musculares Esqueléticas/ultraestructura,
Obesidad/metabolismo,
Distribución Aleatoria,
Ratas Wistar
Abstract Introduction: Literature shows that patients undergoing hemodialysis present poor physical conditioning and low tolerance to exercise. They may also suffer from respiratory dysfunctions. The purpose of this study was to evaluate the effects of neuromuscular electrical stimulation on pulmonary f...
ABSTRACT PURPOSE: To evaluate the effects of levobupivacaine on neuromuscular transmission and neuromuscular blockade produced by pancuronium in vitro. METHODS: Thirty rats were distributed into groups (n = 5) according to the drug used alone or in combination: Group I - levobupivacaine (5 µg.mL-1); ...
Bupivacaína/análogos & derivados,
Bloqueo Neuromuscular,
Unión Neuromuscular/efectos de los fármacos,
Pancuronio/farmacología,
Transmisión Sináptica/efectos de los fármacos,
Anestésicos Locales/farmacología,
Bupivacaína/farmacología,
Diafragma/efectos de los fármacos,
Diafragma/inervación,
Quimioterapia Combinada,
Estimulación Eléctrica/métodos,
Potenciales de la Membrana/efectos de los fármacos,
Potenciales de la Membrana/fisiología,
Modelos Animales,
Unión Neuromuscular/fisiología,
Fármacos Neuromusculares no Despolarizantes/farmacología,
Ratas Wistar,
Transmisión Sináptica/fisiología
ABSTRACTThe objective of this study was to evaluate how Brazilian anesthesiologists are using neuromuscular blockers, focusing on how they establish the diagnosis of postoperative residual curarization and the incidence of complications associated with the use of neuromuscular blockers. A questionnaire w...
A morphological and histochemical study of the human vestibular fold was carried out using routine histological techniques. Seven µm-thick histo logical sections stained with hematoxylin-eosin (HE) and Callej a showed the presence of elastic collagen fibers and seromucous glands in the vestibular fold. ...