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Skin barrier in atopic dermatitis: beyond filaggrin

An. bras. dermatol; 91 (4), 2016
Abstract: Atopic dermatitis is a chronic inflammatory skin disease with a complex pathogenesis, where changes in skin barrier and imbalance of the immune system are relevant factors. The skin forms a mechanic and immune barrier, regulating water loss from the internal to the external environment, and pro...