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Simultaneous determination of clobutinol hydrochloride and doxylamine succinate from syrups by RP HPLC using a new stationary phase containing embedded urea polar groups

Rosa, Paulo Cesar Pires; Jardim, Isabel Cristina Sales Fontes.
Braz. j. pharm. sci; 48 (2), 2012
A new, simple, fast, reproducible and sensitive reversed phase HPLC method, using a new stationary phase containing embedded urea polar groups, has been developed and validated for the simultaneous determination of clobutinol hydrochloride (CLO) and doxylamine succinate (DOX) in syrups. The determination...
Urea/clasificación, 24960/análisis, Doxilamina/clasificación, Cromatografía de Fase Inversa/métodos, Tos
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Carbamide peroxide gel stability under different temperature conditions: is manipulated formulation an option?

Bonesi, Camila de Martini; Ulian, Letícia Storchi; Balem, Paula; Angeli, Valeria Weiss.
Braz. j. pharm. sci; 47 (4), 2011
Nowadays the use of gel containing carbamide peroxide (CP) prepared in Pharmacy is a normal practice in the population. However, the quality of this product is questionable concerning its stability. The aim of this study is was to synthesize and to analyze this drug alone or associated to Carbopol gel th...
Urea/clasificación, Peróxido de Hidrógeno/clasificación, Blanqueamiento de Dientes, Química Farmacéutica, Buenas Prácticas de Manipulación
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