LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Effects of anastrozole on Ki-67 antigen expression in the vaginal epithelium of female rats in persistent estrus

Chagas, Diego Cipriano; Barros-Oliveira, Maria da Conceição; Lopes-Costa, Pedro Vitor; Pereira, Renato de Oliveira; Melo, Mariella de Almeida; Costa-Silva, Danylo Rafhael; Borges, Carine Soares; Viana, Jackeline Lopes; Santos, Alesse Ribeiro dos; Facina, Gil; Silva, Benedito Borges da.

Clinics; 75 (), 2020

OBJECTIVES: Aromatase inhibitors are the first-choice drugs for the treatment of hormone sensitive breast cancer. However, in addition to the scarcity of studies, there are controversies about their effects on vaginal epithelial cell proliferation in rats, especially those in persistent estrus. METHODS:...

Anastrozol/farmacología, Epitelio/efectos de los fármacos, Epitelio/metabolismo, Estro/metabolismo, Antígeno Ki-67/efectos de los fármacos, Antígeno Ki-67/metabolismo, Distribución Aleatoria, Ratas Wistar, Vagina/efectos de los fármacos, Vagina/metabolismo

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Risk assessment for preterm delivery using the fetal fibronectin test associated with the measurement of uterine cervix length in symptomatic pregnant women

Abstract Objective To analyze the use of the measurement of uterine cervix length (MUCL) and the fetal fibronectin (fFN) rapid test as predictors of preterm delivery (PTD) in symptomatic pregnant women assisted at the Santa Casa de Misericórdia de Sobral Maternity Hospital. Methods This was a prospe...