The Human Host Defense Peptide LL-37 Overexpressed in Lung Cell Lines by Methanolic Extract of Valeriana officinalis
Braz. J. Pharm. Sci. (Online); 59 (), 2023
Abstract The present study investigated the effects of valerian methanolic extract and valerenic acid on the expression of LL-37 gene and protein in A549 and MRC5 line cells. After preparing Valerian seeds, sowing them in March 2020, and harvesting the rhizome in October 2020, the extract was prepared fr...
Valeriana/efectos adversos, Extractos Vegetales/efectos adversos, Catelicidinas/efectos adversos, Genes/genética, Cromatografía Líquida de Alta Presión/métodos, ddcs0244440, Células A549/clasificación, Hígado/anomalías, Péptidos Catiónicos Antimicrobianos/agonistas, d0024700, Western Blotting/instrumentación