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Role of genetic variability in Mendelian and multifactorial diseases

Ramírez-Bello, Julián.
Gac. méd. Méx; 155 (5), 2019
The first draft of the human genome sequencing published in 2001 reported a large number of single nucleotide polymorphisms (SNPs). Given that these polymorphisms could practically represent all the variability involved in the susceptibility, protection, severity, among other aspects, of various common d...
Enfermedad/genética, Eliminación de Gen, Marcadores Genéticos, Variación Genética/fisiología, Genoma Humano, Escala de Lod, Mutagénesis Insercional, Mutación, Polimorfismo de Nucleótido Simple, Secuencias Repetidas en Tándem
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Cardiac markers in five different breeds of rabbits (Oryctolagus cuniculus Linnaeus, 1758) used for cardiovascular research

Ferreira, Felipp S; Barretto, Flávia L; Fabres, Arianne; Silveira, Leonardo S; Carvalho, Claudio B.
Pesqui. vet. bras; 36 (8), 2016
Cardiac biomarkers for clinical and experimental heart diseases have previously been evaluated in rabbits. However, several laboratory assays performed and reported with inconsistent results. This study aimed to assess the effects of breed on serum ANP, CRP, and ACE and establish reference interval (RI) ...
Biomarcadores/análisis, Peptidil-Dipeptidasa A/análisis, Péptido Natriurético Encefálico, Variación Genética/fisiología, Proteína C-Reactiva/análisis, Ensayo de Inmunoadsorción Enzimática/veterinaria, Análisis de Varianza
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