LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Effects of nitric oxide on C2C12 cell inflammatory responses and notexin-induced muscle injury

Niu, Shu-liang; Jin, Xiu-Fang; Yang, Tao; Chen, Zhi-Hui; Wang, Guang-Dong; Liang, Ying; Yan, Jie.

Int. j. morphol; 40 (1), 2022

SUMMARY: Skeletal muscle injury is an acute inflammatory condition caused by an inflammatory response. To reduce inflammatory cell infiltration and relieve skeletal muscle injury, efficient treatment is urgently needed. Nitric oxide is a free radical molecule reported to have anti-inflammatory effects. I...

Óxido Nítrico/farmacología, Antiinflamatorios/farmacología, Enfermedades Musculares/inducido químicamente, Venenos Elapídicos/toxicidad, Mioblastos/efectos de los fármacos, Supervivencia Celular, Ratas Sprague-Dawley, Modelos Animales de Enfermedad, Inmunohistoquímica, Ensayo de Inmunoadsorción Enzimática, Reacción en Cadena en Tiempo Real de la Polimerasa, Inflamación, NG-Nitroarginina Metil Éster, Caspasas, Técnicas In Vitro

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Kinetic and toxicological effects of synthesized palladium(II) complex on snake venom (Bungarus sindanus) acetylcholinesterase

Ahmed, Mushtaq; Khan, Shahan Zeb; Sher, Naila; Rehman, Zia Ur; Mushtaq, Nadia; Khan, Rahmat Ali.

J. venom. anim. toxins incl. trop. dis; 27 (), 2021

The venom of the krait (Bungarus sindanus), an Elapidae snake, is highly toxic to humans and contains a great amount of acetylcholinesterase (AChE). The enzyme AChE provokes the hydrolysis of substrate acetylcholine (ACh) in the nervous system and terminates nerve impulse. Different inhibitors inactivate...

Bungarus, Venenos Elapídicos/toxicidad, Biología Sintética, Paladio, Acetilcolinesterasa

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Non-neurotoxic activity of Malayan krait (Bungarus candidus) venom from Thailand

Charoenpitakchai, Mongkon; Wiwatwarayos, Kulachet; Jaisupa, Nattapon; Rusmili, Muhamad Rusdi Ahmad; Mangmool, Supachoke; Hodgson, Wayne C; Ruangpratheep, Chetana; Chanhome, Lawan; Chaisakul, Janeyuth.

J. venom. anim. toxins incl. trop. dis; 24 (), 2018

Envenoming by kraits (genus Bungarus) is a medically significant issue in South Asia and Southeast Asia. Malayan krait (Bungarus candidus) venom is known to contain highly potent neurotoxins. In recent years, there have been reports on the non-neurotoxic activities of krait venom that include myotoxicity...

Bungarus/fisiología, Venenos Elapídicos/toxicidad, Venenos Elapídicos/sangre, Citotoxinas/análisis, Venenos Elapídicos/aislamiento & purificación, Bungarotoxinas/sangre, Riñón/patología

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In vitro hemolytic activity of Bothrops lanceolatus (fer-de-lance) venom

Martins, L. J; de Araújo, P. M. F; Bon, C; Hyslop, S; de Araújo, A. L.

J. venom. anim. toxins incl. trop. dis; 15 (3), 2009

Bothrops lanceolatus venom contains a variety of enzymatic and biological activities. The present work investigated the hemolytic activity of this venom and its phospholipase A2 (PLA2). Bothrops lanceolatus venom (6.7 µg/mL) caused indirect hemolysis of cow, horse, rat and sheep erythrocytes, with horse...

Venenos Elapídicos/toxicidad, Técnicas In Vitro, Productos Biológicos, Fosfolipasas A2, Bothrops lanceolatus, Hemólisis, Enzimas

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