Yamada, Suemy M;
Mendonça, Leonardo O;
Eleuterio, Bruno Prado;
Cambui, Raylane A. G;
Roa, Mariela G. V;
Oliveria, Leonardo A. T;
Castro, Paula L. M;
Castro, Fabio F. M;
Watanabe, A. S;
Pontillo, Alessandra.
Introduction: Previous studies have shown that different types of venoms, such as those from snakes, arachnids, and Hymenoptera insects, can active the inflammasome complex, particularly through the NLRP3 receptor, as seen with the honeybee (Apis mellifera) venom component melittin. Furthermore, inflamma...
Hipersensibilidad al Veneno,
Himenópteros,
Inmunoglobulina E,
Hipersensibilidad,
Interleucina-1,
Insectos,
Ponzoñas,
Venenos de Abeja,
Venenos de Artrópodos,
Venenos de Hormiga,
Avispas
Las orugas del género Lonomia, del orden Lepidoptera y familia Saturnidae, son de interés médico en Sudamérica por ser causantes del lonomismo, tipo de envenenamiento que aumenta cada vez más en Colombia, con tasas de mortalidad de 2,5 %. La severidad es variable y los casos no son de notificación ...
The word venomics was coined to acknowledge the studies that use omics to investigate venom proteins and peptides. Venomics has evolved considerably over the last 20 years. The first works on scorpion or spider venomics were published in the early 2000's. Such studies relied on peptide mass fingerprintin...
Accidents with venomous animals are a public health issue worldwide. Among the species involved in these accidents are scorpions, spiders, bees, wasps, and other members of the phylum Arthropoda. The knowledge of the function of proteins present in these venoms is important to guide diagnosis, therapeuti...
A anafilaxia é uma reação alérgica mais grave e potencialmente fatal. Apresenta-se quase sempre com manifestações cutâneas, acompanhadas por acometimento dos sistemas respiratório, gastrointestinal, nervoso e cardiovascular. Indivíduos de todas as faixas etárias podem manifestar anafilaxia, e s...
Hipersensibilidad a los Alimentos,
Anafilaxia,
Epinefrina,
Diagnóstico,
Hipersensibilidad al Látex,
Hipersensibilidad,
Manifestaciones Cutáneas,
Preparaciones Farmacéuticas,
Recurrencia,
Terapéutica,
Venenos de Artrópodos,
Diagnóstico Diferencial,
PubMed
Peptides obtained from different animal species have gained importance recently due to research that aims to develop biopharmaceuticals with therapeutic potential. In this sense, arthropod venoms have drawn attention, not only because of their toxicity but mainly for the search for molecules with various...
ABSTRACT Patients envenomed by Lonomia sp caterpillars initially experience a mild burning pain, headache, nausea, vomiting, and skin and mucosal hemorrhages. Some patients can rapidly progress to a severe coagulopathy that presents as visceral or intracerebral hemorrhaging. We studied the hemostatic alt...
Lonomia obliqua (Walker, 1855) es una mariposa nocturna de la familia Saturniidae, ampliamente distribuida en selvas tropicales de Sudamérica. Su larva (oruga) se caracteriza por poseer espículas ramificadas puntiagudas a lo largo de su cuerpo, que contienen una mezcla compleja de moléculas tóxicas e...
Antivenenos/uso terapéutico,
Argentina,
Venenos de Artrópodos/sangre,
Mordeduras y Picaduras/terapia,
Brasil,
Hematuria,
Hemorragia/inducido químicamente,
Inmunización Pasiva,
Larva/química,
Larva/clasificación,
Mariposas Nocturnas/química,
Mariposas Nocturnas/clasificación
Hyaluronidases are enzymes that mainly degrade hyaluronan, the major glycosaminoglycan of the interstitial matrix. They are involved in several pathological and physiological activities including fertilization, wound healing, embryogenesis, angiogenesis, diffusion of toxins and drugs, metastasis, pneumon...