To study the effect of 50% ethanol extract of
Bougainvillea xbuttiana
on the enzymatic
activity, cell via
bility and cytokine production provoked by the venom of
Bothrops jararaca
in macro
-
phages. Three assays were used to study the effects of
B. xbuttiana
extract on the dama...
Extractos Vegetales/farmacología,
Venenos de Crotálidos/antagonistas & inhibidores,
Macrófagos/efectos de los fármacos,
Nyctaginaceae/química,
Citocinas,
Ensayo de Inmunoadsorción Enzimática,
Etanol,
Fosfolipasas A2,
Ratones Endogámicos BALB C,
Venenos de Crotálidos/enzimología,
Supervivencia Celular/efectos de los fármacos
Background: The bioactive peptides derived from snake venoms of the Viperidae family species have been promising as therapeutic candidates for neuroprotection due to their ability to prevent neuronal cell loss, injury, and death. Therefore, this study aimed to evaluate the cytoprotective effects of a sy...
Os acidentes por animais peçonhentos, especialmente os acidentes ofídicos, foram incluídos pela Organização Mundial da Saúde (OMS) na lista das doenças tropicais negligenciadas que acometem, na maioria das vezes, populações pobres que vivem em áreas rurais, devido à gravidade constituem um pro...
Yoshida, Edson Hideaki;
Dini, Murilo Melo Juste;
Oliveira, Isadora Caruso Fontana;
Matiello Filho, José Antonio;
Cogo, José Carlos;
Cruz-Hofling, Maria Aliceda;
Grotto, Denise;
Hyslop, Stephen;
Yoshida, Valquíria Miwa Hanai;
Oshima, Franco Yoko.
Abstract Acute kidney injury (AKI) is the major cause of mortality following bites by the South American rattlesnake Crotalus durissus terrificus. We investigated the early onset of Crotalus durissus terrificus venom-induced AKI in rats within 2 h of venom injection and its attenuation by antivenom. Seve...
Introdução: Os acidentes ofídicos são eventos negligenciados em países
tropicais e em desenvolvimento, incluindo o Brasil. Serpentes do gênero
Crotalus são aquelas que produzem os quadros de maior letalidade no
país. Objetivos: Abordar os principais aspectos do acidente por Crotalus,
com ênfase ...
There are few scientific studies that explore the use of medicinal plants for snakebite envenoming in Central America, although plant-based therapies have been traditionally used in the region. This work reviews the studies conducted in Central America to assess the ability of extracts obtained from plan...
Anita, Syahfitri;
Sadjuri, Arif Rahman;
Rahmah, Latri;
Nugroho, Herjuno Ari;
Mulyadi, Mulyadi;
Trilaksono, Wahyu;
Ridhani, Wiwit;
Safira, Nabila;
Bahtiar, Hariman;
Maharani, Maharani;
Hamidy, Amir;
Azhari, Adriansjah.
Background: Several studies have been published on the characterization of Trimeresurus venoms. However, there is still limited information concerning the venom composition of Trimeresurus species distributed throughout Indonesia, which contributes to significant snakebite envenomation cases. The presen...
Abstract. Introduction: The thymus is active mainly during the neonatal and pre-adolescent periods. Objective: To test naïve thymocytes proliferation and monocytes stimulation. Materials and methods: We collected fresh thymus tissue from neonate mice after surgery. Suspension cells were coated onto Fico...
Saravia-Otten, Patricia;
Hernández, Rosario;
Marroquín, Nereida;
García, Gabriela;
Nave, Federico;
Rochac, Lorena;
Genovez, Vicente;
Mérida, Max;
Cruz, Sully M;
Cáceres, Armando;
Gutiérrez, Jose M.
Neurolaena lobata es utilizada tradicionalmente en Centroamérica para tratar la mordedura de serpiente, pero su efectividad para contrarrestar el envenenamiento producido por Bothrops asper ha sido poco estudiada. Se evaluó la capacidad del extracto etanólico de sus hojas para inhibir las actividades ...
Bothrops,
Mordeduras de Serpientes/tratamiento farmacológico,
Extractos Vegetales/farmacología,
Antivenenos/farmacología,
Venenos de Crotálidos/antagonistas & inhibidores,
Inhibidores de Fosfolipasa A2/farmacología,
Extractos Vegetales/uso terapéutico,
Plantas Medicinales,
Guatemala,
Medicina Tradicional,
Proteolisis/efectos de los fármacos,
Coagulación Sanguínea/efectos de los fármacos,
Extractos Vegetales/química,
Hojas de la Planta,
Etanol/uso terapéutico,
Electroforesis en Gel de Poliacrilamida
Silva, Flavio Souza;
Ibiapina, Hiochelson Najibe Santos;
Neves, Juliana Costa Ferreira;
Coelho, Kerolaine Fonseca;
Barbosa, Fabiane Bianca Albuquerque;
Lacerda, Marcus Vinicius Guimarães;
Sachett, Jacqueline Almeida Gonçalves;
Malheiro, Adriana;
Monteiro, Wuelton Marcelo;
Costa, Allyson Guimarães.
Abstract INTRODUCTION: Snakebites in the Brazilian Amazon are caused mostly by snakes from the Bothrops genus and envenomated patients may suffer from tissue complications. METHODS: This study aimed to identify risk factors for severe tissue complications (STC) in patients with Bothrops snakebite in t...
