Home > LILACS - Literatura Latinoamericana y del Caribe de Ciencias de la Salud > Search result

Results: 2

Activation of M1 muscarinic acetylcholine receptors by proline-rich oligopeptide 7a (

Alberto-Silva, Carlos; Pantaleão, Halyne Queiroz; Silva, Brenda Rufino da; Silva, Julio Cezar Araujo da; Echeverry, Marcela Bermudez.
J. venom. anim. toxins incl. trop. dis; 30 (), 2024
Background: The bioactive peptides derived from snake venoms of the Viperidae family species have been promising as therapeutic candidates for neuroprotection due to their ability to prevent neuronal cell loss, injury, and death. Therefore, this study aimed to evaluate the cytoprotective effects of a sy...
Receptores Muscarínicos/química, Oligopéptidos/efectos adversos, Prolina, Venenos de Crotálidos/síntesis química, Estrés Oxidativo
Fulltext

Cytotoxic and inflammatory potential of a phospholipase A2 from Bothrops jararaca snake venom

Cedro, Rafhaella C. A; Menaldo, Danilo L; Costa, Tássia R; Zoccal, Karina F; Sartim, Marco A; Santos-Filho, Norival A; Faccioli, Lúcia H; Sampaio, Suely V.
J. venom. anim. toxins incl. trop. dis; 24 (), 2018
Snake venom phospholipases A2 (PLA2s) have been reported to induce myotoxic, neurotoxic, hemolytic, edematogenic, cytotoxic and proinflammatory effects. This work aimed at the isolation and functional characterization of a PLA2 isolated from Bothrops jararaca venom, named BJ-PLA2-I. Methods and Results:...
Venenos de Crotálidos/síntesis química, Bothrops, Fosfolipasas A2/síntesis química, Citotoxinas, Citotoxicidad Inmunológica
Fulltext