LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Evaluating mmp-2 and tgfß-ri expression in circulating tumor cells of pancreatic cancer patients and their correlation with clinical evolution

Gasparini-Junior, José Luiz; Fanelli, Marcello Ferretti; Abdallah, Emne Ali; Chinen, Ludmilla Thomé Domingos.

ABCD (São Paulo, Impr.); 32 (2), 2019

ABSTRACT Background: Metastasis is common in the diagnosis of pancreatic cancer, and the presence of epithelial-mesenchymal transition markers in circulating tumor cells may suggest worse prognosis. Aim: To correlate the number of circulating tumor cells (CTCs) in the peripheral blood of patients with...

Adenocarcinoma/sangre, Adenocarcinoma/patología, Biomarcadores de Tumor/sangre, Progresión de la Enfermedad, Transición Epitelial-Mesenquimal, Estimación de Kaplan-Meier, Metaloproteinasa 2 de la Matriz/sangre, Clasificación del Tumor, Estadificación de Neoplasias, Células Neoplásicas Circulantes/química, Células Neoplásicas Circulantes/patología, Neoplasias Pancreáticas/sangre, Neoplasias Pancreáticas/patología, Estudios Prospectivos, Receptor Tipo I de Factor de Crecimiento Transformador beta/sangre, Valores de Referencia, Factores de Tiempo, Carga Tumoral, Vimentina/sangre

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Analysis of four serum biomarkers in rheumatoid arthritis: association with extra articular manifestations in patients and arthralgia in relatives

ABSTRACT Objectives: To evaluate the frequency of four serum biomarkers in RA patients and their relatives and identify possible associations with clinical findings of the disease. Methods: This was a transversal analytical study. Anti-cyclic citrullinated peptide (anti-CCP), anti-mutated citrullinated...