Objetivo: investigar o conhecimento de profissionais de saúde presentes em unidades básicas de saúde (UBS’s) sobre o HTLV e as condutas tomadas em caso de infecção. Método:pesquisa quantitativa transversal de abordagem exploratória, sendo realizada por meio de entrevista, com preenchim...
The present study aims to correlate the sample-to-cutoff ratios (S/CO) distributions of reactive results for HTLV-1/2 antibodies with the detection of proviral DNA in a population of blood donor candidates. It was carried out a retrospective data search of 632 HTLV-1/2 reactive samples, submitted to con...
RESUMEN Se buscó determinar la prevalencia de marcadores infecciosos en donantes de un banco de sangre en Perú y valorar si las variables sociodemográficas del donante se asocian con la presencia de estos marcadores. Se realizó un estudio transversal analítico en 5942 donantes de un banco de sangre ...
Pontes, Gemilson Soares;
Ribeiro, Hygor Halyson Figueiredo;
Toro, Diana Mota;
Moura Neto, José Pereira de;
Souza, Victor;
Almeida, Maria Edilene Martins de;
Nascimento, Valdinete Alves do;
Costa, Cristovão Alves da;
Naveca, Felipe Gomes;
Santos, Mike;
Vallinoto, Antonio Carlos Rosário.
Abstract INTRODUCTION: We investigated the prevalence of human T-cell lymphotropic virus types 1 and 2 (HTLV-1/2) infection in patients with hematological diseases from the western Amazon region of Brazil. METHODS: Samples from 306 patients were submitted for the molecular diagnosis of HTLV-1/2 infecti...
Orletti, Maria P.S;
Assone, Tatiane;
Sarnaglia, Glenia Daros;
Martins, Marina Lobato;
Rosadas, Carolina;
Casseb, Jorge;
Taylor, Graham;
Ferreira-Filho, Joaquim B;
Pereira, Fausto E.L;
Miranda, Angélica Espinosa.
ABSTRACT Introduction: Brazil has a high number of HTLV-1/2 infections which are unequally distributed in the country. Most prevalence studies have focused on specific populations, such as blood donors and pregnant women. Some areas, for example the state of Bahia, have robust information about HTLV-1/2...
Abstract INTRODUCTION We present a data analysis and review of recent studies regarding the laboratory diagnosis of human T-lymphotropic virus 1 and 2 (HTLV-1/2) infections in Brazil. METHODS Target populations, available diagnostic serological assays (screening and complementary tests), molecular as...
Provirus mutations of human T-lymphotropic virus 1 (HTLV-1), mostly the lack of the 5= long terminal repeat (LTR) genomic region, have been described and associated with severe adult T cell leukemia/lymphoma (ATLL), non-sense point mutations with low proviral load, and Western blotting indeterminate resu...
The human T-lymphotropic viruses type 1 (HTLV-1) and type 2 (HTLV-2) are endemic and neglected in Brazil, and although these viruses were considered to have prognostic value when associated with HIV, e.g., HTLV-1 has been associated with fast progression and death to AIDS and more cases of lymphoma and n...
Laboratory diagnosis of human T-lymphotropic viruses (HTLV) 1 and 2 infection is
performed by serological screening and further confirmation with serological or molecular assays.
Thus, we developed a loop-mediated isothermal nucleic acid amplification (LAMP) assay for the
detection of HTLV-1/2 in blood s...
