Results: 3

Critical role of metabotropic glutamate receptor 4 in bone marrow-derived dendritic cells in the Th17 cell differentiation and the melanogenesis of B16 cells

Braz. j. med. biol. res; 53 (4), 2020
Vitiligo is an acquired pigmentary disorder resulting from selective destruction of melanocytes. Emerging studies have suggested that T helper cell 17 (Th17) is potentially implicated in vitiligo development and progression. It was recently discovered that metabotropic glutamate receptor 4 (mGluR4) can m...

Vitiligo - Part 1

An. bras. dermatol; 89 (3), 2014
Vitiligo is a chronic stigmatizing disease, already known for millennia, which mainly affects melanocytes from epidermis basal layer, leading to the development of hypochromic and achromic patches. Its estimated prevalence is 0.5% worldwide. The involvement of genetic factors controlling susceptibility t...

studio in vitro e in situ de la respuesta inmune en el eritema discrómico perstans y vitiligo
Study in vitro e in situ of the immune responsein the Erythema dyschromicum perstans and vitiligo

El eritema discrómico perstans (EDP) y el vitiligo son dermatosis pigmentarias cutáneas de etiología desconocida, en las que existen evidencias que sugieren una importante participación del sistema inmune. En el presente trabajo, se estudiaron los infiltrados leucocitarios de ambas enfermedades. La c...