Propranolol inhibits myocardial infarction-induced brown adipose tissue D2 activation and maintains a low thyroid hormone state in rats
Braz. j. med. biol. res; 52 (10), 2019
Considering the recognized role of thyroid hormones on the cardiovascular system during health and disease, we hypothesized that type 2 deiodinase (D2) activity, the main activation pathway of thyroxine (T4)-to-triiodothyronine (T3), could be an important site to modulate thyroid hormone status, which wo...
Tejido Adiposo Pardo/efectos de los fármacos, Tejido Adiposo Pardo/metabolismo, Agonistas Adrenérgicos beta/administración & dosificación, Modelos Animales de Enfermedad, Yoduro Peroxidasa/efectos de los fármacos, Yoduro Peroxidasa/metabolismo, Infarto del Miocardio/metabolismo, Propranolol/administración & dosificación, Ratas Wistar, Tiroxina/sangre, Tiroxina/efectos de los fármacos, Triyodotironina/sangre, Triyodotironina/efectos de los fármacos