Diagnostic laparoscopy is a surgical diagnostic procedure used to examine the organs inside the abdomen by mean of an optic fiber. The patient with acute abdominal pain and with a not clearly etiology, can represent a great challenge at the moment to perform a definitive diagnosis at urgency. The paraclinic studies must be required considering the particular characteristics of each patient and its clinical presentation at the moment of the medical attention. Considering the more frequent indications for the laparoscopic approach, the diagnostic laparoscopy, occupies the third place after the acute appendicitis and the acute cholecistitis. The aim of this report was to consider a casuistic of 356 patients with acute abdominal pain of uncertain etiology, studied by the authors. Of these patients, the 88% were females. From the rsults obtained, it becomes evident that the video diagnostic laparoscopy proved to be an effective technique in the emergency department with benefit for the patients, mainly for acute cases