Adverse drug reactions among patients admitted with infectious diseases at a Brazilian hospital

Rev. Soc. Bras. Med. Trop; 49 (6), 2016
Publication year: 2016

Abstract INTRODUCTION:

Despite the therapeutic benefits of drugs, adverse drug reactions (ADRs) occur.

Method:

We assessed a series of suspected ADRs identified from notifications and intensive monitoring of inpatients from March 2013 to March 2014.

RESULTS:

Skin reactions predominated (31%). Systemic anti-infective agents were implicated in 16 (72%) reactions. Fifteen (68%) ADRs were classified as possible. The implicated drug was not correctly identified by the healthcare team in 12 cases.

CONCLUSIONS:

Some reactions were not correctly attributed to the causative drug(s), suggesting that the use of a validated evaluation method can promote successful identification of causal links between ADRs and drugs.

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