Prevalence and antimicrobial susceptibility of non-fermenting Gram-negative bacilli isolated from clinical samples at a tertiary care hospital
Rev. Soc. Bras. Med. Trop; 50 (2), 2017
Publication year: 2017
Abstract INTRODUCTION:
We compared the prevalence and antimicrobial susceptibility of non-fermenting gram-negative bacilli (NFGNB) isolated from clinical samples at a Brazilian tertiary care hospital in 2008 and 2013.METHODS:
Collected data included patient's name, age, sex, inpatient unit, laboratory record number, type of biological material, culture test result, and antimicrobial susceptibility of isolated strains.RESULTS:
Out of 19,112 culture tests analyzed, 926 (4.8%) were positive for NFGNB. Among these, 45.2% were metallo-beta-lactamase (MBL) producing strains.CONCLUSION:
Between 2008 and 2013, the number of MBL-producing NFGNB isolates increased by 21.5%, which was accompanied by a consequent reduction in susceptibility to antimicrobials.
Antibacterianos/farmacología, Bacterias Gramnegativas/efectos de los fármacos, Bacterias Gramnegativas/enzimología, Bacterias Gramnegativas/aislamiento & purificación, Infecciones por Bacterias Gramnegativas/microbiología, Pruebas de Sensibilidad Microbiana, Persona de Mediana Edad, Prevalencia, Centros de Atención Terciaria, beta-Lactamasas/biosíntesis