Neurological manifestations of dengue in Central Brazil
Rev. Soc. Bras. Med. Trop; 50 (3), 2017
Publication year: 2017
Abstract INTRODUCTION:
The incidence of dengue has increased throughout the 2000s with a consequent global increase in atypical clinical forms.METHODS:
This study reports a series of cases of neurological dengue out of 498 confirmed cases of laboratory dengue in Goiânia, Brazil. Cases were confirmed based on viral RNA detection via polymerase chain reaction or IgM antibody capture.RESULTS:
Neurological symptoms occurred in 5.6% of cases, including paresthesia (3.8%), encephalitis (2%), encephalopathy (1%), seizure (0.8%), meningoencephalitis (0.4%), and paresis (0.4%). DENV-3 was the predominant circulating serotype (93%).CONCLUSIONS:
We reported dengue cases with neurological manifestations in endemic area.
Anticuerpos Antivirales/sangre, Brasil/epidemiología, Dengue/complicaciones, Dengue/epidemiología, Virus del Dengue/genética, Virus del Dengue/inmunología, Encefalitis Viral/epidemiología, Encefalitis Viral/virología, Ensayo de Inmunoadsorción Enzimática, Meningoencefalitis/epidemiología, Meningoencefalitis/virología, Persona de Mediana Edad, Parestesia/epidemiología, Parestesia/virología, Reacción en Cadena de la Polimerasa, ARN Viral/genética