Evaluation of carbapenem-resistant Enterobacteriaceae in a tertiary-level reference hospital in Rio Grande do Sul, Brazil

Rev. Soc. Bras. Med. Trop; 50 (5), 2017
Publication year: 2017

Abstract INTRODUCTION:

The rapid global spread of carbapenem-resistant Enterobacteriaceae (CRE) is a threat to the health system.

METHODS:

We evaluated the antimicrobial susceptibility profiles of 70 CRE isolated in a tertiary hospital in Brazil between August and December 2015, and determined their resistance mechanisms.

RESULTS:

The most prevalent microorganism was Klebsiella pneumoniae (95.7%); it showed high-level resistance to carbapenems (>98%), with sensitivity to colistin (91.4%) and amikacin (98.6%). The bla KPC gene was detected in 80% of the CRE isolates.

CONCLUSIONS:

Evaluation of bacterial resistance contributes to an appropriate treatment, and the reduction of morbimortality and dissemination of resistance.

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