Abstract INTRODUCTION:

Chagas disease is a neglected public health problem in Mexico; however, detailed studies to determine the seroprevalence in some states have not been performed.

METHODS:

A total 1,504 human serum from thirteen communities in Estado de Mexico, were analyzed with three diagnostics techniques.

RESULTS:

The overall seroprevalence was 9.1%, with high prevalence among people aged 51-60 years, while people aged 0-29 years were seronegative against T. cruzi.

CONCLUSIONS:

Our data demonstrated the seroprevalence of T. cruzi in the North of the Estado de Mexico, an area considered as non-endemic; however, epidemiological conditions necessary for natural transmission were found.