Anti-Candida and anti-quorum sensing activity of airborne microorganisms detected by a rapid method
Rev. Soc. Bras. Med. Trop; 52 (), 2019
Publication year: 2019
Abstract INTRODUCTION:
Introducing new antibiotics to the clinic is critical.METHODS:
We adapted a plate method described by Kawaguchi and coworkers in 20131 for detecting inhibitory airborne microorganisms.RESULTS:
We obtained 51 microbial colonies antagonist to Chromobacterium violaceum, purified and retested them, and of these, 39 (76.5%) were confirmed. They comprised 24 bacteria, 13 fungi, and 2 yeasts. Among the fungi, eight (61.5%) produced active extracts. Among the bacterial, yeast, and fungal strains, 17 (44.7%) and 12 (31.6%) were active against Candida albicans and Candida parapsilosis, respectively.CONCLUSIONS:
The proposed screening method is a rapid strategy for discovering potential antibiotic producers.
Microbiología del Aire, Antibacterianos/aislamiento & purificación, Antibacterianos/metabolismo, Antibacterianos/farmacología, Bacterias/aislamiento & purificación, Bacterias/metabolismo, Candida/efectos de los fármacos, Chromobacterium/efectos de los fármacos, Recuento de Colonia Microbiana, Hongos/aislamiento & purificación, Hongos/metabolismo, Percepción de Quorum