Brazilian spotted fever prevention through a nonlethal capybara population control strategy
Rev. Soc. Bras. Med. Trop; 52 (), 2019
Publication year: 2019
Abstract INTRODUCTION:
Brazilian spotted fever (BSF), a lethal tick-borne Rickettsioses (2000 - 2018 >600 human deaths) involving synanthropic capybara as host.METHODS:
We introduced an alternative to mitigate human-capybara conflicts and epidemiologic concerns of BSF. Complex aspects like transmission dynamics, risk areas, host mobility, and birth rate control, were considered to develop a prevention strategy using an anti-GnRH vaccine.RESULTS:
The propositioned immunocontraceptive potentially remove and prevent the spread of BSF from endemic areas.CONCLUSIONS:
We propose the anti-GnRH vaccine as a BSF prevention strategy based on these favorable results.
Brasil, Anticoncepción Inmunológica/métodos, Anticoncepción Inmunológica/veterinaria, Hormona Liberadora de Gonadotropina/inmunología, Regulación de la Población/métodos, Fiebre Maculosa de las Montañas Rocosas/prevención & control, Fiebre Maculosa de las Montañas Rocosas/transmisión, Roedores/parasitología, Garrapatas/microbiología, Vacunas Anticonceptivas/administración & dosificación