Infections and antimicrobial resistance in an adult intensive care unit in a Brazilian hospital and the influence of drug resistance on the thirty-day mortality among patients with bloodstream infections
Rev. Soc. Bras. Med. Trop; 53 (), 2020
Publication year: 2020
Abstract INTRODUCTION:
The present study aimed to determine the incidence of health care-associated infections (HCAIs) and identify the main resistant microorganisms in intensive care unit (ICU) patients in a Brazilian university hospital.METHODS:
A retrospective cohort study was conducted in a Brazilian teaching hospital between 2012 and 2014.RESULTS:
Overall, 81.2% of the infections were acquired in the ICU. The most common resistant pathogenic phenotypes in all-site and bloodstream infections were oxacillin-resistant coagulase-negative staphylococci and carbapenem-resistant Acinetobacter spp. (89.9% and 87.4%; 80.6% and 70.0%), respectively.CONCLUSIONS:
There is an urgent need to focus on HCAIs in ICUs in Brazil.
Antibacterianos/farmacología, Bacteriemia/microbiología, Bacteriemia/mortalidad, Farmacorresistencia Bacteriana, Bacterias Gramnegativas/clasificación, Bacterias Gramnegativas/efectos de los fármacos, Bacterias Gramnegativas/aislamiento & purificación, Bacterias Grampositivas/clasificación, Bacterias Grampositivas/efectos de los fármacos, Bacterias Grampositivas/aislamiento & purificación, Mortalidad Hospitalaria, Incidencia, Unidades de Cuidados Intensivos, Pruebas de Sensibilidad Microbiana, Persona de Mediana Edad, Estudios Retrospectivos, Factores de Tiempo