Preliminary evaluation of the larvicidal activity of extracts and fractions from Ocotea nutans (Nees) Mez against Aedes aegypti

Betim, Fernando Cesar Martins; Oliveira, Camila Freitas de; Montrucchio, Deise Prehs; Miguel, Obdulio Gomes; Miguel, Marilis Dallarmi; Maurer, Juliana Bello Baron; Dias, Josiane de Fátima Gaspari

Preliminary evaluation of the larvicidal activity of extracts and fractions from Ocotea nutans (Nees) Mez against Aedes aegypti

Betim, Fernando Cesar Martins; Oliveira, Camila Freitas de; Montrucchio, Deise Prehs; Miguel, Obdulio Gomes; Miguel, Marilis Dallarmi; Maurer, Juliana Bello Baron; Dias, Josiane de Fátima Gaspari.

Rev. Soc. Bras. Med. Trop; 54 (), 2021

Publication year: 2021

Abstract INTRODUCTION:

Aedes aegypti is the main vector of dengue and yellow fever. Recently, the use of plant-sourced larvicides has gained momentum.

METHODS:

The hydroethanolic extracts and fractions ofOcotea nutansleaves and stems were bioassayed to determine the larvicidal efficacy of these samples.

RESULTS:

S-HEX (hexane fraction from the crude stem extract) demonstrated high potential for controlling third-stage larvae, with an LC50 of 14.14 µg.mL-1 (concentration required to inhibit 50% of the treated larvae). CONCLUSIONS Extracts from O. nutans were effective against third-stage larvae ofA. aegyptiafter 24 h of exposure.

Aedes, Insecticidas/farmacología, Larva, Ocotea, Mosquitos Vectores, Extractos Vegetales/farmacología, Hojas de la Planta

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