Laboratory diagnosis of human T-lymphotropic virus in Brazil: assays, flowcharts, challenges, and perspectives

Revista da Sociedade Brasileira de Medicina Tropical; 54 (1), 2021
Publication year: 2021

Introduction:

We present a data analysis and review of recent studies regarding the laboratory diagnosis of human T-lymphotropic virus 1 and 2 (HTLV-1/2) infections in Brazil.

Methods:

Target populations, available diagnostic serological assays (screening and complementary tests), molecular assays (in-house), causes of false-positive and false-negative results, and flowcharts were analyzed.

Results:

A table presents the target populations, two diagnostic flowcharts (depending on laboratory infrastructure and study population), and recent research that may improve how HTLV-1/2 is diagnosed in Brazil.

Conclusions:

Our results support the implementation of public policies to reduce HTLV-1/2 transmission and its associated diseases.

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