Abstract INTRODUCTION:

We analyzed the trends in primary multidrug-resistant tuberculosis (MDR-TB).

METHODS:

We performed a time series analysis of primary MDR-TB cases reported in the State of Rio de Janeiro (RJ) during 2000-2019. The annual percent change and the average annual percentage change (AAPC) were computed using joinpoint regression analysis.

RESULTS:

The percentage of cases increased from 7.69% in 2000 to 38.42% in 2018. We observed an upward trend during this period (AAPC = 9.4; 95% confidence interval 1.4-18.0, p < 0.001).

CONCLUSIONS:

The trend indicates the increasing occurrence of MDR-TB transmission sources in RJ during 2000-2019.