INTRODUCTION:

Ventilator-associated pneumonia is the sixth nosocomial infection most frequent in Chile. Considering the high mortality associated in this infection, it is important to know the local agents and their respective resistances and susceptibilities to choose and appropriate management.

OBJECTIVE:

Describe the resistance and susceptibilities to antibiotics of the most frequent microorganism in ventilator-associated pneumonia in the Intensive Care Unit at Hospital Regional de Talca.

METHODS:

We studied the resistance and susceptibility to antibiotics to each organism isolated in patients with ventilator-associated pneumonia in the Intensive Care Unit at Hospital Regional de Talca since 2013 to 2016, according to the reports of the Cross Infection Unit at this establishment.

OUTCOMES:

We collected 59 cases and there were 29 cases of them with one microorganism. The highest incidence of ventilator-associated pneumonia was in 2014, while the lowest was in 2015. The most frequent agents isolated were A. baumannii (32,2%), S. aureus (30,1%), P. aeruginosa (10,75%) and K. pneumoniae (10,75%). In general, we found that the highest resistence to antibiotic was to Ceftriaxone, while the highest susceptibility to antibiotic were to Vancomicine and Tigecicline.