Sialolithiasis is one of the most common benign conditions that affect the salivary glands. The disease is characterized by obstruction of the gland parenchyma or ductal system that reduces the salivary flow rate. Most sialoliths occur in the major salivary glands and usually cause acute and chronic infections. Since an inaccurate clinical diagnosis of sialolithiasis is often reported, the aim of this study was to describe the clinical and histopathological features of 11 cases of sialolithiasis over a period of 13 years retrieved from the Oral Pathology Service of the Federal University of Bahia, Brazil. Most sialolithiasis cases involved the major salivary glands and were identified between the 4thand 5th decade of life. There was a slight female predominance. The lesions were usually symptomatic and appeared as a single nodule of firm consistency. The most common location was the submandibular gland, followed by the minor salivary glands (oral mucosa). Surgical excision was performed in all cases. Histopathology revealed a lamellar pattern of calcification of the sialoliths, chronic inflammation, and ductal squamous metaplasia. (AU)