Adjunctive Hyperbaric Oxygen Therapy promotes successful healing in patients with refractory Crohn's disease
Acta cir. bras; 31 (supl.1), 2016
Publication year: 2016
PURPOSE:
To investigate de adjunctive effect of Hyperbaric Oxygen Therapy in a group of patients with refractory Crohn's disease.METHODS:
A total of 29 subjects with refractory Crohn's disease were submitted to daily sessions of Hyperbaric Oxygen Therapy, in a 2800 Sechrist Monoplace Hyperbaric Chamber (Sechrist, USA) pressurized to 2.4 ATA. Each session lasted 2 hours. The endpoint was closure of enterocutaneous fistulas and complete healing of Pyoderma Gangrenosum and perineal Crohn's disease.RESULTS:
A total of 829 HBOT sessions were performed and no complications were noted. Overall success rate was 76% (22 cases). Pyoderma Gangrenosum and enterocutaneous fistulas had the highest successful healing rates (100% and 91%, respectively). Perineal Crohn's disease healing rate was 65%.CONCLUSION:
Adjunctive Hyperbaric Oxygen Therapy promoted satisfactory healing in a group of patients with refractory Crohn's disease.
Enfermedad de Crohn/terapia, Oxigenoterapia Hiperbárica/métodos, Fístula Intestinal/terapia, Piodermia Gangrenosa/terapia, Cicatrización de Heridas, Terapia Combinada, Oxigenoterapia Hiperbárica/estadística & datos numéricos, Estudios Prospectivos, Reproducibilidad de los Resultados, Factores de Tiempo, Resultado del Tratamiento