In this reportthe protective function of nitroglycerin in late myocardial preconditioning against arrhytmias is considered. The results obtained in this study demonstrte thar the reatment with nitroglycerin instead of the preconditioning periods decreases the incidence of arrhythmic episodes similary to the late preconditioning. This is the first report that proves that the late preconditioning against arrhythmias can mimetize pharmacologically with supply of a giver of nitric oxide