p-53: Applications in internal medicine and predictive significance
RBM rev. bras. med; 62 (1/2), 2005
Publication year: 2005
The authors present a review of the properties and functions of the p53 gene and its protein product, along with clinical correlations for tumor development. The genetic expression and prognostic evaluation as well as therapies is reviewed. Also discussed is the importance of mutations in the p53 gene and its protein product in various neoplasias is reviewed.(au)